George Malacinski

CURRICULUM VITAE:

George M. Malacinski, Ph.D.

Professor of Biology, Department of Biology

Indiana University, Bloomington, Indiana 47405

Email: malacins@indiana.edu
Tel. #: (812) 855-1131 / Fax #: (812) 855-6705

EDUCATION:

Public Schools:

Undergraduate:

Doctoral:

Postdoctoral:

Department of Biochemistry Advisor: Dr. W.J. Rutter

PRESENT POSITIONS:

Professor of Biology (semi-retired)

ACADEMIC HONORS:

Boston University

Dean's List

National Science Foundation

Undergraduate Research Grant

B.A. with honors in Biology

Indiana University

Microbiology Training Grant Fellowship

P.H.S. Predoctoral Fellowship

University of Washington

P.H.S. Postdoctoral Fellowship

BOOKS EDITED BY GMM:

Primers in Developmental Biology (Series Editor) - McGraw-Hill Publ. Co.
- Vol. I - Pattern Formation, 626 pp. (1984). GMM ed.
- Vol. II - Molecular Genetics of Mammalian Cells, 384 pp. (1986). GMM ed.
- Vol. III - Developmental Genetics, 503 pp. (1987). GMM ed.
- Vol. IV - Cytoplasmic Organization Systems, 482 pp. (1989). GMM ed.
Advances in Space Research (Vol. 6, #12) Pergamon Press (1986). GMM co-ed
Fundamentals of Space Biology (in press). GMM co-ed.
Developmental Biology of the Axolotl (Oxford Univ. Press, 1989). GMM co-ed.
Molecular Aspects of Early Development (Plenum Press, 1984). GMM co-ed.
American Zoologist (Vol., 18, #2) (1978). GMM ed.
Develop. Biology of Urodeles (Int. J. Dev. Biol.-special issue, 1996) GMM ed.
Teaching Developmental Biology (Int. J. Dev. Biol.-special issue, 2003) GMM ed.
As well, I am the author of a textbook: Essentials of Molecular Biology (2003), Jones and Bartlett Publishers. It is in its 4th edition. Previous editions have been translated into Japanese, Chinese, and Portuguese.

PROFESSIONAL SERVICE:

Member, NSF Developmental Biology Advisory Panel (study section), 1978-1983.
Editorial Boards: International Journal of Developmental Biology (American editor).

PROFESSIONAL SOCIETIES:

International Society of Developmental Biologists
American Association for the Advancement of Science

RESEARCH INTERESTS:

Present:
Bone strengthening and bone molecular biology in collaboration with Prof. Hiroki Yokota, Indiana University School of Medicine.

Sabbatical Leave:
Isolation, identification, and characterization of histone messenger RNA from amphibian embryos; determination, by RNA/DNA hybridization, of the reiteration frequency of the histone genes in Xenopus-- with Max L. Birnstiel, Institute for Molecular Biology, Zurich.

Postdoctoral:
Ontogeny of pancreatic amylase; enzyme purification and preparation of peptide maps; electrophoretic characterization of amylase variants--with Dr. W.J. Rutter.

Ph.D. Research:
Role of orthophosphite in biological phosphorous cycle; physiological and biochemical characteristics of the bacterial oxidation of orthophosphite--under Dr. W.A. Konetzka.

Graduate Research at Michigan State University:
Isolation and characterization of orthophosphite-oxidoreductase from Pseudomonas fluorescens, under Dr. W.A. Wood.

Undergraduate:
Genetic analysis of R1 region and high frequency mutant sites of bacteriophage T4. --under C. Folsome, II.

TEACHING EXPERIENCE:

1979 to present: Professor of Biology
1973 to 1978: Associate Professor Zoology
1968 to 1972: Assistant Professor of Zoology
1966: Visiting Assistant Professor (summer), Indiana University

TEACHING ACTIVITIES:

Each year Prof. M teaches two courses:

E105: Human Cloning and Embryonal Stem Cells: Yes or No?
L322: Writing Workshop in the Logic and Rhetoric of Molecular Biology

TEACHING AWARDS:

1980--First annual outstanding teacher award given by biology senior class.
1985--Alumni distinguished teaching award.
1999--Student Alumni Association Student's Choice Award
1999--National Society of Collegiate Scholars (elected)
2000--College of Arts and Sciences Teaching Excellence Recognition Award
2000--Senior Class Award for Taching Excellence in Biology and Dedication to Undergraduate
2003--Student Alumni Association Student's Choice Award
2004--James P. Holland Award for Exemplary Teaching and Service to Students

EXTRAMURAL AND AVOCATIONAL INTERESTS:

Woodworking, Middle-Eastern textiles, sports, current events, etc.

PUBLICATIONS: (Please note - abstracts/meeting reports, book reviews, etc. not included): Undergraduate

Malacinski, G.M. Fine structure genetic analysis of R1 region of T4 bacteriophage. Proc. East. New England Biology Conference, 1961.

Graduate

Malacinski, G.M. and W.A. Konetzka. Bacterial oxidation of orthophosphite. J. Bacteriol. 91: 578, 1966.

Malacinski, G.M. and W.A. Konetzka. Enzymic basis of the bacterial oxidation of orthophosphite. Bact. Proc., 1966.

Malacinski, G.M. and W.A. Konetzka. Orthophosphite-nicotinamide ademine dinucleotide oxidoreductase from Pseudomonas fluorescens. J. Bacteriol. 93: 1906, 1967.

Postdoctoral

Malacinski, G.M. and W.J. Rutter. Multiple molecular forms of a-amylase from the rabbit. Biochemistry, 8: 4382, 1969.

Indiana University Faculty

1. Gordon, G. and G.M. Malacinski. An improved microinjection apparatus for biochemical embryology. Microchem. J. 15: 685-691, 1970.

2. Malacinski, G.M. Preparative gel electrophoresis of ribonucleic acids. Anal. Biochem. 38: 288-291, 1970.

3. Malacinski, G.M. and G. Gordon. An instrument for slicing and handling radioactive polyacrylamide gels. Chem. Instrum. 3: 89-96, 1971.

4. Malacinski, G.M. Microassay of a-amylase with radioactive substrate. Microchem. J. 16: 296-303, 1971.

5. Malacinski, G.M. Determination of mammalian serum a-amylase with a radioactive substrate assay. Amer. J. Clin. Pat. 56: 623-626, 1971.

6. Malacinski, G.M. Genetic control of qualitative changes in protein synthesis during early amphibian (Mexican axolotl) embryogenesis. Devel. Biol. 26: 442-451, 1971.

7. Malacinski, G.M. The Naples Zoological Station. Bioscience 21: 884, 1971.

8. Malacinski, G.M. The deployment of maternal template during early amphibian embryogenesis. J. Exptl. Zool. 181: 409-420, 1972.

9. Malacinski, G.M. Identification of a presumptive morphogenetic determinant from the amphibian oocyte germinal vesicle nucleus. Cell Differentiation 1: 253-254, 1972.

10. Malacinski, G.M. The amphibian egg: a new tool in biochemistry. Chemistry 46: 10-13, 1973.

11. Lutzeler, I.E. and G.M. Malacinski. Modulations in the electrophoretic spectrum of newly synthesized protein in early axolotl (Ambystoma mexicanum) development. Differentiation 2: 287-297, 1974.

12. Malacinski, G.M. and A.J. Brothers. Mutant genes in the Mexican axolotl. Science 184: 1142-1147. 1974.

13. Malacinski, G.M. Biological properties of a presumptive morphogenetic determinant from the amphibian oocyte germinal vesicle nucleus. Cell Differentiation 3: 31-44, 1974.

14. Malacinski, G.M. Histone synthesis in amphibian oocytes and early embryos. Experientia 30: 610-613, 1974.

15. Malacinski, G.M., C.D. Allis, and H-M. Chung. Correction of developmental abnormalities resulting from localized ultra-violet irradiation of an amphibian egg. J. Exptl. Zool. 189: 249-255, 1974.

16. Chung, H-M and G.M. Malacinski. Repair of damage to a cytoplasmic localization in the amphibian egg. Proc. Natl. Acad. Sci. 72: 1235- 1239, 1975.

17. Lehrner, L.M. and G.M. Malacinski. Genetic and structural studies of chicken a-amylase isozymes and their modified forms, and structural studies of hog amylase. 3rd Int'l. Cont. Isozymes, Academic Press, IV: 727-743, 1975.

18. Lehrner, L.M. and G.M. Malacinski. Biochemical genetics of a-amylase isozymes of the chicken pancreas. Biochemical Genetics 13: 145-173, 1975.

19. Malacinski, G.M., H. Benford, and H-M. Chung. Association of an ultraviolet irradiation sensitive cytoplasmic localization with the future dorsal side of the amphibian egg. J. Exptl. Zool. 191: 97-110, 1975.

20. Jacob, E., G.M. Malacinski, and M.S. Birnstiel. Reiteration frequency of the histone genes in the genome of the amphibian, Xenopus laevis. Eur. J. Biochem. 69: 45-54, 1976.

21. Lehrner, L.M. and G.M. Malacinski. Analysis of the structural forms of a- amylase present in chicken (Gallus domesticus) pancreatic duct juice and intestinal lumen. Comp. Biochem. Physiol. 53B: 61-66, 1976.

22. Chung, H-M. and G.M. Malacinski. The Mexican axolotl (Ambystoma mexicanum) as experimental material for studies in embryology. I. General Introduction. Kor. J. Zool. 19: 49-56, 1977.

23. Chung, H-M. and G.M. Malacinski. The Mexican axolotl as experimental material for studies in embryology. II. Developmental genetics. Kor. J. Zool. 20: 149-157, 1977.

24. Chung, H-M. and G.M. Malacinski. Developmental lesions in amphibian embryos induced by ultraviolet irradiation of the fertile egg. Kor. J. Zool. 20: 109-122, 1977.

25. Malacinski, G.M., A.J. Brothers, and H-M. Chung. Destruction of components of the neural induction system of the amphibian egg with ultra-violet irradiation. Develop. Biol. 56: 24-39, 1977.

26. Malacinski, G.M. and A.J. Brothers. Developmental genetics of the early embryo (meeting report). Bioscience 27: 279, 1977.

27. Malacinski, G.M., H-M. Chung, and B. Youn. Further characterization of the effects of ultraviolet irradiation of the amphibian egg. Experientia 34: 883-884, 1977.

28. Humphrey, R.R., G.M. Malacinski, and H-M. Chung. Developmental studies on an apparent cell-lethal mutant gene-ut-in the Mexican axolotl, (Ambystoma mexicanum). Cell Differentiation 7: 47-59, 1978.

29. Karn, R.C. and G.M. Malacinski. Comparative biochemistry and genetics of animal a- amylases. In, Advances in Comparative Physiology and Biochemistry, ed. by E.O. Lowenstein. Academic Press, Vol. 7, pp. 1- 103, 1978.

30. Malacinski, G.M., B. Ryan, and H-M. Chung. Surface coat movements in the unfertilized amphibian egg. Differentiation 10: 101-107, 1978.

31. Malacinski, G.M. The Mexican axolotl, (Ambystoma mexicanum): Its biology and developmental genetics and its autonomous cell-lethal genes. American Zoologist 18: 195-206, 1978.

32. Malacinski, G.M. R.R. Humphrey--dedication. American Zoologist 18: 191-193, 1978.

33. Malacinski, G.M. Introduction to Developmental Genetics of Mexican Axolotl Symposium. American Zoologist 18: 189-193, 1978.

34. Malacinski, G.M. R.R. Humphrey memorial. Anat. Rec. 192: 130-131, 1978.

35. Sinclair, J.H., C. Carroll, and G.M. Malacinski. Composition and behavior of the nucleolar organizer of the nucleolar variant of axolotls. Review and comparison to other systems. American Zoologist 18: 225-236, 1978.

36. Malacinski, G.M. and J. Spieth. Maternal effects in the Mexican axolotl (Ambystoma mexicanum). British Soc. Dev. Biol. Symp. 4: 241-267, 1979.

37. Chung, H-M. and G.M. Malacinski. The establishment of the dorsal/ventral polarity of the amphibian egg-use of UV irradiation and egg rotation as probes. Devel. Biol. 80: 120-133, 1980.

38. Frost, S. and G.M. Malacinski. Pigment mutants in the Mexican axolotl. Develop. Gen. 1: 271-294, 1980.

39. Malacinski, G.M., H-M. Chung, and M. Asashima. The association of primary embryonic organizer activity with the future dorsal side of amphibian eggs and early embryos. Devel. Biol. 77: 449-462, 1980.

40. Youn, V.W. and G.M. Malacinski. Action spectra for U.V. inactivation of the cytoplasmic components required for neural induction in amphibian eggs. J. Exptl. Zool. 211: 369-377, 1980.

41. Youn, B.W., R. Keller, and G.M. Malacinski. An atlas of early notochord and somite morphogenesis in amphibian embryos. J. Embryol. exp. Morph. 59: 223-247, 1980.

42. Chung, H-M. and G.M. Malacinski. A comparative study of the effects of egg rotation and UV irradiation on anuran vs. urodele amphibian eggs. Differentiation 18: 185-189, 1981.

43. Malacinski, G.M. and H-M. Chung. Establishment of the site of involution at novel locations on the amphibian embryo. J. Morph. 167: 147-159, 1981.

44. Malacinski, G.M. and B.W. Youn. The dynamics of early pattern formation in amphibian embryogenesis--use of ultraviolet irradiation as a probe. Neth. J. Zool. 31: 38-49, 1981.

45. Malacinski, G.M., B.W. Youn, and A. Jurand. Tissue interactions during structure pattern formation in amphibia. Scanning Electron Microscopy: 1981/II (pp. 307-318).

46. Malacinski, G.M. and B.W. Youn. Neural plate morphogenesis and axial stretching in Ònotochord-defectiveÓ Xenopus laevis embryos. Develop. Biol. 88: 352-357, 1981.

47. Radice, G.P., A.W. Neff, and G.M. Malacinski. The intracellular responses of frog eggs to novel orientations to gravity. The Physiologist 24: #6, Suppl. pp. S79-S80, 1981.

48. Youn, B.W., and G. M. Malacinski. Axial structure development in ultraviolet-irradiated (notochord-defective) amphibian embryos. Develop. Biol. 83: 339-352, l981.

49. Youn, B.W. and G.M. Malacinski. Somitogenesis in the amphibian Xenopus laevis: Scanning electron microscopic analysis of intrasomitic cellular arrangements during somite rotation. J. Embryol. exp. Morph. 64: 23-43, 1981.

50. Youn, B.W. and G.M. Malacinski. Comparative analysis of amphibian somite morphogenesis: Cell rearrangement patterns during rosette formation and myoblast fusion. J. Embryol. exp. Morph. 66: 1-26, 1981.

51. Chung, H-M., and G.M. Malacinski. Pattern formation during early amphibian development: Embryogenesis in inverted anuran and urodele eggs. Develop. Biol. 93: 444-452, 1982.

52. Malacinski, G.M. and B.W. Youn. The structure of the amphibian notochord, and a re-evaluation of its presumed role in early embryogenesis. Differentiation 21: 13-21, 1982.

53. Chung, H-M., and G.M. Malacinski. Reversal of developmental competence in inverted amphibian eggs. J. Embryol. exp. Morph. 73: 207-220, 1983.

54. Jurand, A. and G.M. Malacinski. Changes in the ultrastructure of the notochord sheath and neural tube cells in Xenopus laevis embryos after ultraviolet irradiation. Acta Embryol. Morphol. Exper. 4: 3-16, 1983.

55. Malacinski, G.M. and B.W. Youn. Neural tube (canal) morphogenesis in notochordless amphibian (Xenopus laevis) embryos. Proc. Soc. Expt. Biol. med. 174: 316-321, 1983.

56. Neff, A.W., G.M. Malacinski., M. Wakahara, and A. Jurand. Pattern formation in amphibian embryos prevented from undergoing the classical Òrotation responseÓ to egg activation. Develop. Biol. 97: 103- 112, 1983.

57. Smith, J.C., and G.M. Malacinski. The origin of the mesoderm in Xenopus laevis, an Anuran, and the Axolotl (Ambystoma mexicanum), a Urodele. Develop. Biol. 98: 250-254, 1983.

58. Chung, H-M. and G.M. Malacinski. Experimentally provoked double axes formation in Xenopus laevis embryos. Kor. J. Zool. 27: 93-102, 1984.

59. Frost, S.K., F. Briggs, and G.M. Malacinski. A color atlas of pigment genes in the Mexican axolotl (Ambystoma mexicanum). Differentiation 26: 182-188, 1984.

60. Malacinski, G.M. Axis specification in amphibian eggs. In, Pattern Formation, Malacinski, G.M. and Bryant, S.V., eds., Macmillan, New York, pp. 435-456, 1984.

61. Malacinski, G.M. and A.W. Neff. The influence of gravity on the process of development in animal systems. In Advances in Space Research. Pergamon Press, Oxford, England 4 (#12): 315-323, 1984.

62. Meuler, D.C., and G.M. Malacinski. Protein synthesis patterns during early amphibian embryogenesis. In Òmolecular Aspects of Early DevelopmentÓ, Malacinski, G.M., and Klein, W.H., eds., Plenum Press, New York, pp. 267-288. 1984.

63. Neff, A.W., and G.M. Malacinski. Reversal of pattern formation in inverted amphibian eggs. The Physiologist 25: 119-120, #6, Suppl. 1982.

64. Neff, A.W., R.C. Smith, H-M. Chung, and G.M. Malacinski. Influence of clinostat rotation on fertilized amphibian egg pattern specification. The Physiologist 27: 139-140 (#6, Suppl.), 1984.

65. Neff, A.W., M. Wakahara, A. Jurand, and G.M. Malacinski. Experimental analyses of cytoplasmic rearrangements which follow fertilization and accompany symmertrization of inverted Xenopus eggs. J. Embryol. exp. Morph. 80: 197-224,1984.

66. Wakahara, M., A.W. Neff, and G.M. Malacinski. Topology of the germ plasm and development of primordial germ cells in inverted amphibian eggs. Differentiation 26: 203-210, 1984.

67. Wakahara, M., A.W. Neff, and G.M. Malacinski. Delayed fertilization of anuran amphibian (Xenopus) eggs leads to reduced numbers of primordial germ cells. Gamete Res. 9: 361-373, 1984.

68. Malacinski, G.M. Embryonic Induction. In McGraw-Hill Encyclopedia of Science and Technology 6: 301-302.

69. Chung, H-M. and G.M. Malacinski. SEM study of sperm penetration in polyspermic urodele amphibian (Ambystoma mexicanum) eggs . Kor. J. Zool. 28: 1-8, 1985.

70. Cuny, R., and G.M. Malacinski. Banding differences between tiger salamander and axolotl chromosomes. Can. J. Genet. Cytol. 27: 510- 514, 1985.

71. Malacinski, G.M. sperm penetration and the establishment of the dorsal/ventral polarity of the amphibian egg. In "Biology of Fertilization", ed. by Monroy and Metz, Academic Press, New York: pp. 82-127, 1985.

72. Malacinski, G.M. and D. Barone. Towards understanding paternal extragenic contributions to early amphibian pattern specific ation: the axolotl ts-1 gene as a model system. J. Embryol. exp. Morph. 89 (suppl.) 53-68, 1985.

73. Meuler, D.C. and G.M. Malacinski. An analysis of protein synthesis patterns during early embryogenesis of the urodele-Ambystoma mexicanum. J. Embryol. exp. Morph. 89: 71-92, 1985.

74. Neff, A.W., G.M. Malacinski, and H-M. Chung. Microgravity simulation as a probe for understanding early Xenopus pattern specification. J. Embryol. exp. Morph. 89: 259-274, 1985.

75. Smith, R.C., Neff, A.W., and G.M. Malacinski. Response of amphibian egg non-yolk cytoplasm to gravity orientation. The Physiologist 28: 91-92, 1985.

76. Wakahara, M., Neff, A.W., and G.M. Malacinski. Development of delayed gastrulae and permanent blastulae from inverted Xenopus laevis eggs. Acta Embryol. Morph. Exp. 6: 193-209, 1985.

77. Chung, H.M., Neff, A.W., and G.M. Malacinski. Characterization of a new amphibian mutant gene-pinhead-in the axolotl (Ambystoma mexicanum). Environ. Mutagen. Carcin. 6: 91-104, 1986.

78. Cuny, R., and G.M. Malacinski. Axolotl retina and lens development: mutual tissue stimulation and autonomous failure in the eyeless mutant retina. J. Embryol. exp. Morph. 96: 151-170, 1986.

79. Eagleson, G.W., and G.M. Malacinski. A scanning electron microscopy and histological study of the effects of the mutant eyeless (e/e) gene upon the hypothalamus in the mexican axolotl Ambystoma mexicanum. Shaw. Anat. Rec. 215: 317-327, 1986.

80. Malacinski, G.M. Amphibian developmental genetics. In Developmental Genetics . Malacinski, G.M. ed., MacMillian, New York, pp. 393- 411,1988.

81. Malacinski, G.M., and A.W. Neff. Effects of gravity perturbation on developing animal systems. Adv. Space Res. 6 (#12): 29-36, 1986.

82. Neff, A.W., Smith, R.C., and G.M. Malacinski. Amphibian egg cytoplasm response to altered G forces and gravity orientation. Adv. Space Res. 6 (#12): 21-28, 1986.

83. Smith, R.C., Neff, A.W., and G.M. Malacinski. Accumulation, organization and deployment of oogenetically derived Xenopus yolk/nonyolk proteins. J. Embryol. exp. Morph. 97 (suppl.) 45-64, 1986.

84. Carrasco, A.C., and G.M. Malacinski. Localization of Xenopus homeo-box gene transcripts during embryogenesis and in the adult nervous system. Develop. Biol. 121: 69-81, 1987.

85. Malacinski, G.M., Neff, A.W., and M. Wakahara. Upside-down amphibian eggs: What can they tell us about early embryonic pattern specification? The Biologist 66: 70-87, 1987.

86. Armstrong, J.B., Duhon, S.T., and G.M. Malacinski. Raising the axolotl in captivity. In The Axolotl in developmental Biology. Oxford University Press. pp. 220-227, 1989.

87. Asashima, M., Malacinski, G.M., and S.C. Smith. surgical manipulation of embryos. In, The Axolotl in Developmental Biology. Oxford University Press. pp. 252-263, 1989.

88. Bordzilovskaya, N.P., Dettlaff, Duhon, S.T., and G.M. Malacinski. Developmental stage series of axolotl embryos. In The Axolotl in Developmental Biology. Oxford University Press. pp. 201-219, 1989.

89. Chung, H.-M., Neff, A.W., and G.M. Malacinski. Autonomous death of amphibian (Xenopus laevis) cranial myotomes. J. Exptl. Zool. 251: 290-299, 1989.

90. Cuny, R., and G.M. Malacinski. The eyeless (e) gene: Effects on embryonic development. In, The Axolotl in Development al Biology. Oxford University Press. pp. 132-142, 1989.

91. Frost, S.K., Neff, A.W., and G.M. Malacinski. Primary and long-term culture of axolotl cells. In The Axolotl in Developmental Biology. Oxford University Press pp. 244-254, 1989.

92. Malacinski, G.M. 1989. Axenic Culture. In Encyclopedia of Science and Technology, McGraw-Hill.

93. Malacinski, G.M. Developmental genetics of the axolotl. In The Axolotl in Developmental Biology. Oxford University Press. pp. 102-109, 1989.

94. Malacinski, G.M., and A.W. Neff. The amphibian egg as a model system for analyzing gravity effects. Adv. Space Res. 9: 169-176, 1989.

95. Malacinski, G.M., and A.W. Neff. Redundancy within developmental processes. In Cytoplasmic Organization Systems, McGraw Hill, 1989. pp. 123-154.

96. Malacinski, G.M., Neff, A.W., Alberts, J.R., and Y.A. Souza. Developmental biology in the realm of outer space. BioScience 38: 314-320, 1989.

97. Malacinski, G.M., Neff, A.W., Radice, G., and H.-M. Chung. Amphibian somite development: Contrasts of morphogenetic and molecular differentiation patterns between the laboratory archetype species Xenopus (anurna) and axolotl (urodele). Zool. Sci. 6: 1-14, 1989.

98. Neff, A.W., Malacinski, G.M., and H.-M. Chung. Amphibian (urodele) somitogenesis displays transitory anterior/posterior and medial/lateral myotome differentiation patterns within individual somites. Developmental Biology: 132: 529-543, 1989.

99. Radice, G.P. and G.M. Malacinski. Expression of myosin heavy chain transcripts during Xenopus laevis development. Develop. Biol. 133: 562-568, 1989.

100. Radice, G.P., Neff, A.W., Shim, Y-H., Brustis, J.-J., and G.M. Malacinski. Developmental histories in amphibian myogenesis. Intl. J. Dev. Biol. 33: 325-343, 1989.

101. Malacinski, G.M. Reproduction, development, and growth of animals in space. In, Fundamentals of Space Biology: Japan. Sci. Soc. Press. pp. 123-138, 1990.

102. Neff, A.W., Wakahara, M., and G.M. Malacinski. Bifurcation of the amphibian embryo's axis: Analysis of variation in response to egg centrifugation. Intl. J. Dev. Biol. 34: 391-398, 1990.

103. Malacinski, G.M., and A.W. Neff. Developmental biology in space. Encly. Brit. Ann. Year Book of Sci., pp. 69-81, 1992.

104. Yokota, H., A.W. Neff and G.M. Malacinski. Altering the position of the first horizontal cleavage furrow of the amphibian (Xenopus) egg reduces embryonic survival. Intl. J. Dev. Biol. 36: 527-535. 1992.

105. Neff, A.W., Wakahara, M., Yokota, H., and G.M. Malacinski. Understanding the organization of the amphibian egg cytoplasm: Gravitational force as a probe. Adv. Space Res.: 12: 175-180.

106. Yokota, H., A.W. Neff and G.M. Malacinski. Early development of Xenopus embryos is affected by simulated gravity. Adv. Space Res. 14: 249-255, 1994.

107. Neff, A.W., H. Yokota, H.-M. Chung, M. Wakahura and G.M. Malacinski. Early amphibian (anuran) morphogenesis is sensitive to novel graitational fields. Develop. Biol. 155: 270-274, 1993.

108. Chung, H.-M., H. Yokota, A. Dent, G.M. Malacinski and A.W. Neff. The location of the third cleavage plane of Xenopus embryos partitions morphogenetic information in animal quartets. Int. J. Devel. Biol. 38: 421-428, 1994.

109. Yokota, H., A.W. Neff, and G.M. Malacinski. Analysis of Experimental and quantitative Parameters employed to asses the effects of novel gravity forces on the amphibian egg. Biological Sciences in Space 7: 85-100, 1994.

110. Ludolph, D.C., Neff, A.W., Mescher, A.L., Malacinski, G.M., Parker, M.A. and Smith, R.C. Overexpression of XMyoD or XMyF5 in Xenopus embryos nduces the formation of enlarged myotomes through recruitment of cells of nonsomatic lineage. Develop. Biol. 166: 18-33, 1994.

111. Ludolph, D.C., A.W. Neff, M.A. Parker, A.L. Mescher, R.C. Smith, and G.M. Malacinski. Cloning and expression of the axolotl proto- oncogene ski. Biochim. Biophys. Acta 1260: 102-104, 1995.

112. Sun, H.B., Neff, A.W., Mescher, A.L., and G.M. Malacinski. Expression of the axolotl homologue of mouse chaperonin t-complex protein-1 during early development. Biochim. Biophys. Acta 1260: 157-166, 1995.

113. Malacinski, G.M., and H.-M. Chung. Urodele (e.g., axolotl) embryos in the undergraduate laboratory class: an essay describing a multifaceted learning experience. Int. J. Devel. Biol. 40: 901-905, 1996

114. Ariizumi, T. Komazaki, S., Asashima, M., and G.M. Malacinski. Activin treated urodele ectoderm: a model experimental system for cardiogenesis. Int. J. Devel. Biol. 40: 715-718, 1996.

115. Malacinski, G.M., Bessho, jT., Yokota, C., Fukui, A., and Asashima, M. An essay on the similarities and differences between inductive interactions in anuran and urodele embryos. CMLS Cell. mol. life sci 53: 410-417 (1997).

116. Asashima, M., Kinoshita, K., Ariizumi, T., and G.M. Malacinski. Role of activin and other peptide growth factors in body patterning in the early amphibian embryo. Int. Rev. Cytol 191: 2-52, 1999.

117. Ariizumi, T., Takano, K., Asashima, M., and G.M. Malacinski. Bioassays of inductive interactions in amphibian development. Protocols Dev. Biol. 135 (1): 89-112, 2000.

118. Asashima, M.K., Ariizumi, T.K., Takashashi, S., and G.M. Malacinski. Bioassays for studying the role of the peptide growth factor activin in early amphibian embryogenesis. Protocols Dev. Biol. (in press).

119. Asashima, M., Yokota C., Takahashi, S., Lau, C.L., and G.M. Malacinski. Peptide growth factors in amphibian embryogenesis: intersection of modern molecular approaches with traditional inductive interaction paradigms. Int. J. Devel. Biol. 40: 1-10, 1999.

120. Malacinski, G.M, Neff, A.W., and Yokota, H. Researching embryos in microgravity: past, present, and future. J. Jpn. Soc. Microgravity 15: (suppl. 11) 672-677, 1999.

121. Malacinski, G.M., Wassersug, R., and Ijiri, K. Biological Science in Space: Enhancing knowledge while developing a global civic-responsibiltiy ethic. J. Jpn Soc. Microgravity 15: (suppl. 11) 595-597,1999.

122. Yokota, H., Ikeuchi, M., Neff, A.W., and Malacinski, G.M. Frontiers in Biology: nanobiotech lab for the space station. J. Jpn. Soc. Microgravity 15: (suppl. 11) 598-601, 1999.

123. Asashima, M., Ariizumi, T., and G.M. Malacinski. In vitro control of organogenesis and body patterning by activin during early amphibian development. Comp. Biochem. Physiol. 126 (B): 169-178, 2000.

124. Malacinski, G.M., Ariizumi, T., and M. Asashima. Work in progess: the Renaissance in amphibian embryology. Comp. Biochem. Physiol. 126 (B): 179-187, 2000.

125. Yokota, H., Sun, H.B., and G.M. Malacinski. Future opportunities for life science programs in space. Kor. J. Biol. Sci. 4: 239-243, 2000.

126. Sun, H.B., Malacinski, G.M., and H. Yokota. Promoter competition assay for analyzing gene regulation in joint-tissue engineering. Front. Biosci. 7: 169-174, 2002.

127. Ariizumi, T., Masayoshi, K., Yokota, C., Takano, K., Fukuda, K., Moriyama, N., Malacinski, G.M., and Asashima, M. Amphibian in vitro heart induction: a simple and reliable model for the study of vertebrate cardiac development. Int. J. Develop. Biol. 47: 405-410, 2003.

128. Zhang, P., Malacinski, G., Yokota, H. Joint loading modality: Its application to bone formation and fracture healing. Br. J. Sports Med. (BJSM Online First, published Nov. 29, 2007.

129. Zhang, P., Hamamura, K., Yokota, H., Malacinski, G.M. Pulsating joint loading (PJL) as a candidate therapy for bone strengthening and wound healing in sports medicine. Exercise Sports Science Revs (Amer College Sports Med): Submitted (2008).

Teaching Publications

(1) Zell, P.W. and G.M. Malacinski. Impediments to developing collaborative learning strategies: The input vs. output conflict. J. Sci. Ed. Tech. 3: 107-114. 1994.

(2) Malacinski, G.M., and P.W. Zell. Manipulating the "invisible": Learning molecular biology using inexpensive models. Amer. Biol. Teacher: 58: 428-432 (October) 1996.

(3) Malacinski, G.M., and P.W. Zell. Learning molecular biology means more than memorizing the formula for tryptophan. J.Coll. Sci. Teaching. 25(Dec 95/Jan96): 198-202, 1996.

(4) Malacinski, G.M. Student-oriented learning: an inquiry-based developmental biology lecture course. Intl. J. Develop. Biol. 47: 135-140, 2003.

(5) Malacinski, G.M., Yokota, H., and Akay, H.U. Integrating the traditionally trained mechanical engineer (problem-solver) into modern medical research projects. Proc. Amer. Soc. Engineering Ed. Pp. 1-5 (2007).